Book between plants with supplement capsules

Knowledge Blog > Micronutrient Encyclopedia

Nettle

What are the effects of stinging nettle?

Themen dieses Blogartikels:

Table of Contents

Hardly any plant is as underestimated as the stinging nettle – for most, it is primarily known as a stinging weed by the roadside. Yet, for centuries, the healing properties of the stinging nettle have been among the most traditional topics in European naturopathy.

Definition: What is stinging nettle?

The stinging nettle (Urtica dioica) belongs to the nettle family (Urticaceae).¹ The nettle owes its name to the Latin "uro"/"urere" (to burn, to singe) – a direct reference to the fine stinging hairs on its leaves and stems, which cause a characteristic burning sensation upon contact.¹

Not least because of its diverse range of applications, the stinging nettle was named Medicinal Plant of the Year 2022 by the Theophrastus Association, an award the association has presented annually for over 20 years.² In addition to the stinging nettle, there is the closely related dwarf nettle (Urtica urens), which remains smaller but features similar active ingredients and is also valued as a medicinal herb.³ Both species of nettle are primarily found in moist soil, meadows, and along paths, as well as on fallow land.⁶

Different parts of the plant are used – and this is an important point that many are unaware of: the leaf, root, and seeds of the nettle contain different compositions of active ingredients.⁴ The root, for example, contains different substances such as phytosterols, which play almost no role in the leaf.⁵ The remainder of this article – like the form of extract typically used in dietary supplements – refers exclusively to the leaf of the stinging nettle.

What ingredients are in stinging nettle?

Nettle leaves contain a whole range of interesting ingredients that distinguish this medicinal plant:

  • Minerals: including sodium, iron, and potassium⁷
  • Vitamins: including vitamin C (ascorbic acid)⁸ as well as vitamin A and vitamin E⁹
  • Flavonoids: including quercetin glycosides and rutin, which are attributed with antioxidant properties¹⁰

This combination is considered the basis for the traditionally attributed effects of the stinging nettle. Important for context: "traditionally used" means that a plant has been used in experiential medicine over a long period – this is different from the body of evidence for a classic, isolated active ingredient.

Nettle and water balance: the best-known effect

Arguably the best-known aspect of the nettle's effect is its relationship to the body's water balance. The aerial parts of the nettle – primarily the leaves – are traditionally described as diuretic and associated with the urinary tract.¹¹ The nettle's diuretic property is not attributed to a single active ingredient, but rather to the interaction of several components such as potassium salts and flavonoids.¹²

To better understand this connection, it is worth looking at something we already explained in more detail in our basic article on acid-base balance: the pH level of your blood is regulated automatically and very stably around the clock. What is actually measurable and can be influenced by external factors, however, is excretion via the kidneys – which is visible in urine, not blood. Supported urinary excretion is closely linked to precisely this excretion pathway.

Traditionally, nettle leaves are often used in combination with parsley. Parsley leaves are also traditionally described as diuretic.¹³ The combination of both plants has a long history in traditional herbalism because their properties complement each other in the same direction.

Display

  • Complex to support the balance of the acid-base household¹
  • Mineral base consisting of zinc (as zinc citrate), potassium, magnesium, calcium & silicon, as well as potassium and sodium bicarbonate
  • Over 1 g of amino acids – with L-arginine, L-ornithine, L-citrulline & glycine
  • Nettle leaf, parsley herb, and bamboo extract – traditionally associated with the urinary tract
  • Free from fillers or additives
  • Developed with doctors & experts

Can stinging nettle help with "detoxing"?

Your body is busy around the clock eliminating metabolic waste – your liver, kidneys, intestines, skin, and lungs are primarily responsible for helping you with this. When we speak of "detoxifying" or "detox," we generally mean supporting these very natural processes.

Nettle leaves are traditionally among the herbs mentioned in this context. You can find more on the topic of detoxification, the organs involved, and how you can support your body in everyday life in our foundational article on detox.

A note on classification: The diuretic property of nettle (see above) is its best-documented effect and differs from general "detoxification" – while both are related via excretion, they are not the same thing. Furthermore, for structured detox cures in the narrower sense: the scientific evidence for them is controversial, even if many people find them helpful for their well-being, for instance when feeling exhausted.

Nettles and joints: a long-standing connection

Beyond water balance, there is a second, officially recognized traditional application for nettle leaves or nettle herb: the relief of minor joint pain. According to the European Medicines Agency (EMA), this is among the plant's traditional indications.²² This connection to joint complaints, arthritis, and rheumatism has a long history in folk medicine – for generations, nettle has been used both internally as a tea and externally for this purpose.²³

Interestingly: While the minerals and potassium salts it contains are the primary focus regarding water balance (see above), the traditional use for joint complaints is more closely associated with the flavonoids found in nettle, which are attributed with anti-inflammatory properties.²³ However, similar to its use for water balance, the following applies: the evidence regarding traditional use is something different from efficacy confirmed by controlled clinical studies in the modern sense.

In practice, nettle is therefore often not found alone, but as one building block among several in more comprehensive plant complexes for the musculoskeletal system – often together with other traditionally known natural substances such as frankincense or curcuma, as well as with targeted micronutrients for cartilage and connective tissue metabolism.

Display

  • Complex with the four central cartilage/synovial building blocks: chondroitin sulfate, glucosamine sulfate, collagen hydrolysate & hyaluronic acid
  • Vitamin C contributes to normal collagen formation for the normal function of cartilage
  • With stinging nettle, frankincense & turmeric – plant substances traditionally associated with joint stress
  • Manganese contributes to normal connective tissue formation, zinc & selenium to the protection of cells from oxidative stress
  • Supplemented with MSM as well as vitamins E, D3 & K2

Nettle for skin and hair

The stinging nettle is one of the silicon-rich plants and, in this context, is traditionally associated with the skin and connective tissue.¹⁴ A study on human hair follicles in an organ culture model also showed that a nettle extract could promote hair shaft growth and delay the transition into the resting phase (catagen phase).¹⁵ Such cell and organ culture studies provide initial indications, but cannot be easily transferred to use in humans.

Nettles and hormones: What’ s in the root?

As described at the beginning, the root of the stinging nettle contains different substances than the leaf, including phytosterols.⁵ In the leaf itself, which is the focus of the rest of the article, this aspect plays a significantly minor role. If you would like to learn more about the topic of hormones, read our blog article "Which hormones are there?".

Stinging nettle and histamine, why the stinging nettle stings at all

An interesting side note: The stinging hairs of the nettle—the very part that causes those familiar welts on the skin when touched—contain, among other things, histamine and acetylcholine.¹⁶ This is the reason for the characteristic burning sensation upon contact with the skin and has nothing to do with any effect on the body after consumption. Incidentally, drying or heating significantly alters the stinging hairs themselves, which is why dried nettle leaves lose their stinging effect.

These three topics are complex enough that we will explore them in greater detail elsewhere.

Stinging nettle in cuisine and history: from Hildegard von Bingen to wild herb cooking

In addition to its role as a medicinal plant in naturopathy, the stinging nettle also has a long culinary tradition: harvested as a wild herb, young leaves can be prepared like spinach as a vegetable in spring – for example in soups.¹⁷ In the garden, the stinging nettle is also known as nettle manure, a traditionally produced liquid fertilizer.¹⁹

Historically, the use of the stinging nettle goes back even further: in the 12th century, the Benedictine nun Hildegard of Bingen described the plant in her work "Physica" – cooked, the stinging nettle is useful for nutrition because it cleanses the stomach and removes mucus from it.¹⁸ This historical association with gastrointestinal complaints shows how long the stinging nettle has been part of traditional medicine – though this does not equate to scientific confirmation in the modern sense. To this day, the stinging nettle remains a staple of many herb gardens and naturopathic associations as a medicinal herb.

In which situations is stinging nettle traditionally used?

In the previous description, several situations have already been mentioned in which nettle traditionally plays a more frequent role:

  • During the transition to spring, when young nettle leaves are traditionally harvested for a spring cleanse
  • When your fluid balance is a concern in everyday life – for example on warm days
  • As part of a conscious, varied diet, if you are interested in wild herbs in the kitchen

Nettle tea, extract & what you should look out for in everyday life

Nettle tea, prepared from dried leaves, is certainly the best known – one to two teaspoons of dried leaves per cup, covered with hot water and left to steep for a few minutes.²⁰ Traditionally, nettle tea is a popular spring tonic when the first young leaves can be harvested.¹⁷ In addition, nettle leaves are also available as an extract, for example in capsule or drop form – a more concentrated alternative to classic nettle tea.

Important for all forms of application that aim to support excretion – whether as nettle tea or as an extract: Drinking enough fluids is always part of it, so that the body can actually transport what is to be excreted.

How much nettle do you need per day?

Since stinging nettle is not a classic nutrient, there is no recommended intake from the German Nutrition Society (DGE). However, it is important to understand where the European Medicines Agency (EMA) draws the line between dietary supplements and medicinal products: stinging nettle leaves are only classified as a traditional herbal medicinal product at a single dose of 2 to 4 grams of dried leaves per tea infusion, up to three times daily—that is, a total daily amount of approximately 8 to 12 grams.²¹

Dietary supplements are deliberately dosed below this pharmacologically active amount so that no medicinal effect occurs and their classification as dietary supplements is maintained. The amount contained in any given product is therefore significantly lower than the medicinal dosages mentioned here—the recommended intake on the product's packaging is always the decisive factor. According to the EMA, use is not recommended for children under 12 years of age, and mild gastrointestinal discomfort may occasionally occur with medicinally dosed amounts.²¹ In case of uncertainty, it is, as always, worth consulting a doctor.

What should you keep in mind when taking it?

Despite their natural properties, it is worth considering a few points regarding stinging nettles:

  • Impaired heart or kidney function: Due to their diuretic effect, use without medical consultation is not recommended if these organs are already impaired, as this can affect fluid balance.²²
  • Diuretic medication: Anyone already taking prescribed diuretics should speak with a doctor before additionally taking stinging nettle supplements, as the diuretic effect could be intensified.²²
  • Known hypersensitivity: Anyone who is allergic to plants in the nettle family should avoid using them.²³
  • Pregnancy and breastfeeding: Due to their diuretic effect, it is generally recommended to consult a doctor before consumption.²³
  • Practical tip for harvesting: If you are harvesting fresh nettle leaves yourself, it is best to wear gloves – the stinging hairs are still effective even on the fresh plant.

Conclusion

The stinging nettle is far more than just a stinging weed. Its minerals, vitamins, and flavonoids make the stinging nettle a medicinal plant with a long tradition – especially in relation to the water balance, but also beyond that. As is so often the case in naturopathy, the rule applies: traditional experience is valuable, but it does not replace a critical look at what is actually proven.

More blog articles on this topic

Warum Elektrolyte im Sport entscheidend sind für Energie, Muskeln & Hydration
Why Electrolytes are Crucial in Sports for Energy, Muscles & Hydration

Discover why electrolytes in sports mean more than just "water balance" and what role they play for your body.

Read article
Mineralstoffe, Spurenelemente und Elektrolyte: Der große Überblick
Minerals, trace elements and electrolytes: the big picture
Nothing works in the body without them: minerals and trace elements are the driving forces behind many vital processes. In this article, you can find out which of these substances are essential and where you can get them from.
Read article
Elektrolyte im Sport: 7 Tipps, wann und wie du sie für maximale Performance nutzt
Electrolytes in Sports: 7 Tips on When and How to Use Them for Maximum Performance

How can you use electrolytes to achieve your training goals and when is the best time to take them?

Read article
Tipps für entspannte Wechseljahre: Ernährung, Sport und Self-Care
Tips for a relaxed menopause: nutrition, exercise and self-care

What phases of menopause are there and what exactly happens in the body? Here you can find out how to cope with this time in a relaxed way.

Read article
Männergesundheit unter Druck: Warum Spermienqualität und Testosteron jeden Mann betreffen
Men's Health Under Pressure: Why Sperm Quality and Testosterone Affect Every Man

How can micronutrients support sperm quality, testosterone, and blood circulation?

Read article
Testosteron natürlich steigern: Do’s & Don’ts für Testosteron im Gleichgewicht
Naturally Boost Testosterone: Do's & Don'ts for Balanced Testosterone

What are the symptoms of low testosterone & how can you naturally boost your testosterone?

Read article
Herzgesundheit durch Omega 3: Alles, was du über die Vorteile und richtige Dosierung wissen solltest
Heart health through Omega-3: Everything you should know about the benefits and correct dosage.

What impact does Omega 3 have on heart health? What are the benefits of Omega 3, and what ratio of EPA to DHA is appropriate?

Read article
Schwaches Herz stärken: Tipps und natürliche Mittel für dein Herz
Strengthen a weak heart: Tips and natural remedies for your heart

A strong heart helps you stay fit for a long time and improves your overall well-being. This article introduces you to routines and natural remedies for everyday life that can help you strengthen your heart.

Read article
Aminosäuremangel: Symptome, Ursachen und was du dagegen tun kannst
Amino acid deficiency: symptoms, causes and what you can do about it
Amino acids play an important role in the human body. In this article, you will find out what amino acids are, what they mean for the body and what symptoms you can use to recognize a deficiency. You will also get tips on how to remedy your amino acid deficiency.
Read article
Was sind Aminosäuren und was bewirken sie?
What are amino acids and what do they do?
Amino acids are protein building blocks and are important for the muscles, among other things. Find out which amino acids are available and where you can get them.
Read article
Aminosäuren & Sport: Darum brauchst du Proteinbausteine
Amino acids & sport: why you need protein building blocks
Amino acids are important for success in training. Find out all about their function and how to take them correctly.
Read article
Mehr Power durch smarte Aminosäuren – neue wissenschaftliche Perspektiven
More power through smart amino acids – new scientific perspectives

What is a smart amino acid supply, tailored to your body? Learn how to bring your body into balance.

Read article
Kreatin zum Muskelaufbau: Wie effektiv ist es wirklich für dein Training?
Creatine for muscle building: How effective is it really for your training?

Athletes need strong muscles. We will tell you whether creatine effectively supports muscle building & your training & how it works.

Read article
Mehr Muskelmasse durch Epigenetik & Mitochondrien-Power
More muscle mass through epigenetics & mitochondrial power
In this article, we'll dive deep into the science behind muscle building, including the latest findings in epigenetics and mitochondrial function.
Read article
Welche Hormone gibt es - und wie beeinflussen sie Mann und Frau?
What hormones are there - and how do they affect men and women?
Without hormones, your body is in radio silence: find out all about your body's messenger substances, hormonal differences between men and women and how the hormonal cycle changes over time.
Read article
Einschlafprobleme? Ursachen und Tipps zum Einschlafen
Problems falling asleep? Causes and tips for falling asleep
What are the typical causes of problems falling asleep? And what can help? We have the best tips for falling asleep for you.
Read article
L-Arginin
L-Arginine

What is L-arginine, what function does it have in the human body, and how is it related to men's health?

Read article
Glycin
Glycine

What are glycine and Trimethylglycine (betaine): what functions and effects does it have on your well-being, and in which foods is it particularly abundant?

Read article
Magnesium
magnesium
What is magnesium, what function and effect does it have on your well-being?
Read article
Silicium
Silicium
What is silicium, what function and effect does it have on your well-being?
Read article
Calcium
Calcium
What is calcium, what function and effect does it have on your well-being?
Read article
Tryptophan
Tryptophane

What is Tryptophane, what function and effect does it have on your well-being?

Read article

This encyclopedia entry is based on carefully researched sources:

Bibliography & Sources

  1. Joshi BC, Mukhija M, Kalia AN. Pharmacognostical review of Urtica dioica L. Int J Green Pharm. 2014;8(4):201.
  2. PTAheute. Medicinal plant of the year 2022: Stinging nettle. 2022.
  3. European Medicines Agency (EMA), Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Urtica dioica L., Urtica urens L., folium. 
  4. Bhusal KK, Magar SK, Thapa R, Lamsal A, Bhandari S, Maharjan R, Shrestha S, Shrestha J. Nutritional and pharmacological importance of stinging nettle (Urtica dioica L.): A review. Heliyon. 2022;8(6):e09717.
  5. Samakar B, Mehri S, Hosseinzadeh H. A review of the effects of Urtica dioica (nettle) in metabolic syndrome. Iran J Basic Med Sci. 2022;25(5):543-553. 
  6. Grauso L, de Falco B, Lanzotti V, Motti R. Stinging nettle, Urtica dioica L.: botanical, phytochemical and pharmacological overview. Phytochem Rev. 2020;19:1341-1377. 
  7. Joshi BC, Mukhija M, Kalia AN. Pharmacognostical review of Urtica dioica L. Int J Green Pharm. 2014;8(4):201.
  8. Samakar B, Mehri S, Hosseinzadeh H. A review of the effects of Urtica dioica (nettle) in metabolic syndrome. Iran J Basic Med Sci. 2022;25(5):543-553. 
  9. Gül S, Demirci B, Başer KHC, Akpulat HA, Aksu P. Chemical composition and in vitro cytotoxic, genotoxic effects of essential oil from Urtica dioica L. Bull Environ Contam Toxicol. 2012;88(5):666-671. doi:10.1007/s00128-012-0535-9
  10. Bhusal KK, Magar SK, Thapa R, Lamsal A, Bhandari S, Maharjan R, Shrestha S, Shrestha J. Nutritional and pharmacological importance of stinging nettle (Urtica dioica L.): A review. Heliyon. 2022;8(6):e09717. 
  11. Ait Haj Said A, El Otmani IB, Derfoufi S, Benmoussa A. Highlights on nutritional and therapeutic value of stinging nettle (Urtica Dioica). Int J Pharm Pharm Sci. 2015;7(10):8-14.
  12. Samakar B, Mehri S, Hosseinzadeh H. A review of the effects of Urtica dioica (nettle) in metabolic syndrome. Iran J Basic Med Sci. 2022;25(5):543-553. 
  13. Agyare C, Appiah T, Boakye YD, Apenteng JA. Petroselinum crispum: A Review. In: Kuete V, ed. Medicinal Spices and Vegetables from Africa. Academic Press; 2017:527-547.
  14. Mohta A, et al. Efficacy and safety of mesoporosil treatment in enhancing skin firmness, hydration, and elasticity: an 84-day clinical trial. Cosmoderma. 2025.
  15. Myagmar K, Lkhagvasuren E, Semchin M. Hair Growth Promoting Effect of Urticadioica L. Cent Asian J Med Sci. 2018;4(3):187-193. doi:10.24079/cajms.2018.09.004
  16. Samakar B, Mehri S, Hosseinzadeh H. A review of the effects of Urtica dioica (nettle) in metabolic syndrome. Iran J Basic Med Sci. 2022;25(5):543-553. 
  17. Jan KN, Zarafshan K, Singh S. Stinging nettle (Urtica dioica L.): a reservoir of nutrition and bioactive components with great functional potential. J Food Meas Charact. 2017;11:423-433. 
  18. Heilkraft der Alpen. Stinging nettle (citing Hildegard of Bingen, "Physica", 12th century). https://www.heilkraftderalpen.org/wissen/heilpflanzen/brennnessel
  19. Asgarpanah J, Mohajerani R. Phytochemistry and pharmacologic properties of Urtica dioica L. J Med Plants Res. 2012.
  20. Kräuterkontor. Stinging Nettle Blog. 
  21. European Medicines Agency (EMA), Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Urtica dioica L., Urtica urens L., folium. https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-urtica-dioica-l-urtica-urens-l-folium_en.pdf
  22. European Medicines Agency (EMA), Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Urtica dioica L., Urtica urens L., folium. 
  23. Asgarpanah J, Mohajerani R. Phytochemistry and pharmacologic properties of Urtica dioica L. J Med Plants Res. 2012.
  24. ScienceDirect Topics. Urtica Dioica – an overview (citing WHO 1999, Kirchhoff 1983). 
  25. ND Health Facts. Urtica dioica.